Potential of a deep eutectic solvent in silver nanoparticle fabrication for antibiotic residue detection

• Le Hong Tho,
• Bui Xuan Khuyen,
• Ngoc Xuan Dat Mai and
• Nhu Hoa Thi Tran

Beilstein J. Nanotechnol. 2024, 15, 426–434, doi:10.3762/bjnano.15.38

• ). At the limit of detection (LOD) of 10−8 M, the SERS spectrum clearly shows emerging peaks, the highest enhancement factor (EF) of which reaches 6.29 × 107, proving the NFT residue tracing capability of the Ag NPs-DES substrate. These peaks correspond to vibrations of characteristic groups of NFT as

Nanoarchitectonics of photothermal materials to enhance the sensitivity of lateral flow assays

• Elangovan Sarathkumar,
• Rajasekharan S. Anjana and
• Ramapurath S. Jayasree

Beilstein J. Nanotechnol. 2023, 14, 988–1003, doi:10.3762/bjnano.14.82

• nanocomposite was used for the preconcentration of antigen in the sample using a magnetic field and Au was used as a photothermal signal amplification probe. This method enabled the quantitative determination of OTA using a portable thermal camera with a limit of detection (LOD) of 0.12 pg·mL−1 [81]. Graphene

A graphene quantum dots–glassy carbon electrode-based electrochemical sensor for monitoring malathion

• Sanju Tanwar,
• Aditi Sharma and
• Dhirendra Mathur

Beilstein J. Nanotechnol. 2023, 14, 701–710, doi:10.3762/bjnano.14.56

• concentration for malathion detection is: Using the equation kSb/m [35], where Sb represents standard deviation of the peak current of the blank, m represents the slope of the calibration plot, k has a value of 3, the limit of detection (LOD) was calculated to be 0.62 nM. In a similar manner, the limit of

Metal-organic framework-based nanomaterials as opto-electrochemical sensors for the detection of antibiotics and hormones: A review

• Akeem Adeyemi Oladipo,
• Saba Derakhshan Oskouei and
• Mustafa Gazi

Beilstein J. Nanotechnol. 2023, 14, 631–673, doi:10.3762/bjnano.14.52

• and challenges It is crucial to assess the performance of sensors during development using standard metrics such as selectivity, sensitivity, the limit of detection (LOD), and response time. Selectivity refers to a sensor’s capacity to respond to a narrow range of target analytes while resisting

• (ELISA), radioimmunoassay (RIA), surface-enhanced Raman spectroscopy (SERS), and capillary electrophoresis are common analytical techniques used to qualitatively or quantitatively determine pharmaceuticals in various matrices because they are sensitive (Figure 2), have a significant tolerable limit of

• detection (LOD), and are selective in many cases. However, they have a number of shortcomings. For example, in order to increase the sensitivity of the established immunoassays, Mitchell and Lowe [20] and Wu et al. [21] used the ELISA technique for the analysis of testosterone and progesterone, respectively

Combining physical vapor deposition structuration with dealloying for the creation of a highly efficient SERS platform

• Adrien Chauvin,
• Walter Puglisi,
• Damien Thiry,
• Cristina Satriano,
• Rony Snyders and
• Carla Bittencourt

Beilstein J. Nanotechnol. 2023, 14, 83–94, doi:10.3762/bjnano.14.10

• mostly built to detect low concentration of molecules in a solution. Therefore, RhB solutions were diluted in order to reach the limit for which the signal of the molecule cannot be seen, corresponding to the limit of detection (LoD) of our material (Figure 8a). For this part, AlAg30 thin films dealloyed

Rapid and sensitive detection of box turtles using an electrochemical DNA biosensor based on a gold/graphene nanocomposite

• Abu Hashem,
• M. A. Motalib Hossain,
• Ab Rahman Marlinda,
• Mohammad Al Mamun,
• Khanom Simarani and
• Mohd Rafie Johan

Beilstein J. Nanotechnol. 2022, 13, 1458–1472, doi:10.3762/bjnano.13.120

• linearity in the range of 1 × 10−11 to 5 × 10−6 M. The limit of detection (LOD) of the developed electrochemical DNA biosensor was calculated and found to be 0.85 × 10−12 M, which implies that the performance of the developed biosensor is quite satisfactory to detect box turtles in a sample. The previously

Orally administered docetaxel-loaded chitosan-decorated cationic PLGA nanoparticles for intestinal tumors: formulation, comprehensive in vitro characterization, and release kinetics

• Sedat Ünal,
• Osman Doğan and
• Yeşim Aktaş

Beilstein J. Nanotechnol. 2022, 13, 1393–1407, doi:10.3762/bjnano.13.115

• of DCX was measured by UV spectrophotometry (Shimadzu UV-1800 UV–vis spectrophotometer, Shimadzu corporation, Japan) at 230 nm (λmax). Validation of the spectrophotometric method was carried out. Linearity, accuracy, precision, reproducibility, limit of detection (LOD), and limit of determination

A nonenzymatic reduced graphene oxide-based nanosensor for parathion

• Sarani Sen,
• Anurag Roy,
• Ambarish Sanyal and
• Parukuttyamma Sujatha Devi

Beilstein J. Nanotechnol. 2022, 13, 730–744, doi:10.3762/bjnano.13.65

• ] + 3.7526 (R² = 0.9936) for 3–15 nM, Ip (μA) = 19.176 [PT] + 4.2723 (R² = 0.9367) for 0.03–0.15 nM. The corresponding sensitivity was found to be 50.5 μA·μM−1·cm−2 with a wide linear range for quantification of PT. The limit of detection (LOD = [(3 * standard deviation of blank)/slope of the lowest range of

Detection and imaging of Hg(II) in vivo using glutathione-functionalized gold nanoparticles

• Gufeng Li,
• Shaoqing Li,
• Rui Wang,
• Min Yang,
• Lizhu Zhang,
• Yanli Zhang,
• Wenrong Yang and
• Hongbin Wang

Beilstein J. Nanotechnol. 2022, 13, 549–559, doi:10.3762/bjnano.13.46

• change of GNPs-GSH-RH6G2 from colorless to pink when Hg2+ was added (Figure 5e). The fluorescence response showed a good linear relationship in the concentration range of 0.025–0.3 mM. The linear regression equation was F = 86.96c − 27.76 (R2 = 0.9914) (c represents Hg2+ concentration), and the limit of

• detection (LOD) was calculated to be 8.4 μM (S/N = 3). In Table 1 the analytical performance of the constructed sensors is compared with other reported methods and with sensing techniques based on GNPs. The results indicate that the proposed strategy has good selectivity and acceptable sensitivity compared

Zinc oxide nanostructures for fluorescence and Raman signal enhancement: a review

• Ioana Marica,
• Fran Nekvapil,
• Maria Ștefan,
• Cosmin Farcău and
• Alexandra Falamaș

Beilstein J. Nanotechnol. 2022, 13, 472–490, doi:10.3762/bjnano.13.40

• detection of dopamine, an enhancement factor of Au–ZnO NRs greater than 1.2 × 104 was obtained. The 3D SERS substrates based on Ag/ZnO/Au structures showed a higher SERS enhancement factor of 1 × 1010 and a limit of detection (LOD) down to 10−16 for rhodamine 6G (R6G) [68]. In this case, the charge transfer

A non-enzymatic electrochemical hydrogen peroxide sensor based on copper oxide nanostructures

• Irena Mihailova,
• Vjaceslavs Gerbreders,
• Marina Krasovska,
• Eriks Sledevskis,
• Valdis Mizers,
• Andrejs Bulanovs and
• Andrejs Ogurcovs

Beilstein J. Nanotechnol. 2022, 13, 424–436, doi:10.3762/bjnano.13.35

• calibration curve for the dependence of the catalytic current values on the concentration of H2O2. A linear relationship was obtained in the range from 10 to 1800 µM (R = 0.99874). The sensitivity of the obtained CuO electrode is 439.19 μA·mM−1. The calculated limit of detection (LOD) is 1.34 μM, assuming

• 439.19 μA·mM−1 and the calculated limit of detection (LOD) was 1.34 μM. The electrochemically active surface area was calculated to be 6.5 cm2. Sensitivity testing showed a lack of electrochemical response to the most common interfering substances, showing the high selectivity of this electrode. This

Differences in surface chemistry of iron oxide nanoparticles result in different routes of internalization

• Barbora Svitkova,
• Vlasta Zavisova,
• Veronika Nemethova,
• Martina Koneracka,
• Miroslava Kretova,
• Filip Razga,
• Monika Ursinyova and
• Alena Gabelova

Beilstein J. Nanotechnol. 2021, 12, 270–281, doi:10.3762/bjnano.12.22

• parameters for Fe determination were set as follows: wavelength 248.3 nm, slit width 0.2 nm, flame type: acetylene–air, flow: 2.0 L/min for acetylene and 13.5 L/min for air, deuterium background correction, method of the calibration curve in the range 0.1–10 mg/L. The limit of detection (LOD) and limit of

Ultrasensitive detection of cadmium ions using a microcantilever-based piezoresistive sensor for groundwater

• Dinesh Rotake,
• Anand Darji and
• Nitin Kale

Beilstein J. Nanotechnol. 2020, 11, 1242–1253, doi:10.3762/bjnano.11.108

• with a limit of detection (LOD) of 0.56 ng (2.78 pM), which perfectly describes its excellent performance over other reported techniques. Many researchers used nanoparticle-based sensors for the detection of heavy metal ions, but daily increasing usage and commercialization of nanoparticles are rapidly

• the WHO limit of 3 μg/L. Keywords: BioMEMS; heavy metal ions (HMIs); limit of detection (LOD); microcantilevers; microfluidics; micro-electromechanical systems (MEMS); piezoresistive sensors; SAM (self-assembled monolayers); World Health Organization (WHO); Introduction Water is fundamentally

Selective gas detection using Mn₃O₄/WO₃ composites as a sensing layer

• Yongjiao Sun,
• Zhichao Yu,
• Wenda Wang,
• Pengwei Li,
• Gang Li,
• Wendong Zhang,
• Lin Chen,
• Serge Zhuivkov and
• Jie Hu

Beilstein J. Nanotechnol. 2019, 10, 1423–1433, doi:10.3762/bjnano.10.140

• /WO3 material can be consider as a prospective material for quantitative gas detection. It could be inferred from the fitting lines that the limit of detection (LOD) of the 3 atom % Mn3O4/WO3 based gas sensor for H2S, NH3 and CO are 0.0022, 0.0627 and 0.4141 ppm, respectively. But it is very difficult

Janus-micromotor-based on–off luminescence sensor for active TNT detection

• Ye Yuan,
• Changyong Gao,
• Daolin Wang,
• Chang Zhou,
• Baohua Zhu and
• Qiang He

Beilstein J. Nanotechnol. 2019, 10, 1324–1331, doi:10.3762/bjnano.10.131

• ) + 24.45. The inset image in Figure 3d shows that a linear relationship exists between the luminescence intensity of the Janus UCNP capsule motors and the natural logarithm of the TNT concentration. The corresponding limit of detection (LOD) is calculated to be 2.4 ng mL−1 according to the equation LOD

Biomimetic synthesis of Ag-coated glasswing butterfly arrays as ultra-sensitive SERS substrates for efficient trace detection of pesticides

• Guochao Shi,
• Mingli Wang,
• Yanying Zhu,
• Yuhong Wang,
• Xiaoya Yan,
• Xin Sun,
• Haijun Xu and
• Wanli Ma

Beilstein J. Nanotechnol. 2019, 10, 578–588, doi:10.3762/bjnano.10.59

• × 107. The limit of detection (LOD) for CV was as low as 10−11 M, demonstrating the ultrahigh sensitivity of the Ag-G.b.-20 substrate. In addition, the Ag-G.b.-20 substrate has an outstanding reproducibility across the entire area with the maximum value of relative standard deviation (RSD) of less than

• violet (CV) with a limit of detection (LOD) of 10−11 M. The 3D finite-difference time-domain (3D-FDTD) simulation results suggest that the simulated electromagnetic field enhancement of Ag-G.b.-20 is close to the experimental value. Meanwhile, the Ag-G.b.-20 nanohybrids exhibited good stability and

Colorimetric detection of Cu²⁺ based on the formation of peptide–copper complexes on silver nanoparticle surfaces

• Gajanan Sampatrao Ghodake,
• Surendra Krishna Shinde,
• Rijuta Ganesh Saratale,
• Avinash Ashok Kadam,
• Ganesh Dattatraya Saratale,
• Asad Syed,
• Fuad Ameen and
• Dae-Young Kim

Beilstein J. Nanotechnol. 2018, 9, 1414–1422, doi:10.3762/bjnano.9.134

• calibration curve, correlation coefficients (R2), and limit of detection (LOD) were studied using coordination peptides number approach. In all three instances, a linear correlation existed between the absorbance at 520 nm and the Cu2+ concentration over the ranges of 0.08–0.4, 0.08–0.72, and 0.08–1.44 µM Cu2

Fiber optic sensors based on hybrid phenyl-silica xerogel films to detect n-hexane: determination of the isosteric enthalpy of adsorption

• Jesús C. Echeverría,
• Ignacio Calleja,
• Paula Moriones and
• Julián J. Garrido

Beilstein J. Nanotechnol. 2017, 8, 475–484, doi:10.3762/bjnano.8.51

• ) directly relates to the dispersion of the results. The largest COV was for the response measured at 5 and 10 hPa. The limit of detection (LoD) was calculated by the propagation of errors approach, which includes the variability of the blank measurements and the uncertainty of the sample measurements. where

Comparison of four functionalization methods of gold nanoparticles for enhancing the enzyme-linked immunosorbent assay (ELISA)

• Paula Ciaurriz,
• Fátima Fernández,
• Edurne Tellechea,
• Jose F. Moran and
• Aaron C. Asensio

Beilstein J. Nanotechnol. 2017, 8, 244–253, doi:10.3762/bjnano.8.27

• ELISA limit of detection (LOD). Some strategies have been explored to enhance sensitivity, such as redox complexes, electroactive molecules and metal ions [6]. Along these lines, several nanotechnology-based strategies have been proposed involving nanoparticle-based solutions [5][7][8][9][10][11][12

Hydrophilic silver nanoparticles with tunable optical properties: application for the detection of heavy metals in water

• Paolo Prosposito,
• Federico Mochi,
• Erica Ciotta,
• Mauro Casalboni,
• Fabio De Matteis,
• Iole Venditti,
• Laura Fontana,
• Giovanna Testa and
• Ilaria Fratoddi

Beilstein J. Nanotechnol. 2016, 7, 1654–1661, doi:10.3762/bjnano.7.157

• concentration of 1 ppm at room temperature. Our system showed sensibility mainly to nickel (II) ions. For this type of ion, we tested the sensitivity as a function of the ion concentration in the range 1.0–0.1 ppm and we estimated a limit of detection (LOD) of 0.3 ppm. Results and Discussion Silver nanoparticle

Graphene-enhanced plasmonic nanohole arrays for environmental sensing in aqueous samples

• Christa Genslein,
• Peter Hausler,
• Eva-Maria Kirchner,
• Rudolf Bierl,
• Antje J. Baeumner and
• Thomas Hirsch

Beilstein J. Nanotechnol. 2016, 7, 1564–1573, doi:10.3762/bjnano.7.150

• continuous gold film (Figure 6). For the nanohole array with a D/P of 0.43, saturation is almost reached at 5 µM (97% according to the Langmuir fit) and a roughly 12-fold enhancement of the maximum signal response compared to a continuous gold film is observed. Therefore, a 10-times better limit of detection

• (LOD) of ca. 20 nM is found when measuring with substrates with D/P = 0.43 compared to a continuous gold film (ca. 190 nM). The concentration covers the guideline values of the World Health Organization in fresh and drinking water for bis(2-ethylhexyl)phthalate (3–40 nM), the most widespread phthalate

Voltammetric determination of polyphenolic content in pomegranate juice using a poly(gallic acid)/multiwalled carbon nanotube modified electrode

• Refat Abdel-Hamid and
• Emad F. Newair

Beilstein J. Nanotechnol. 2016, 7, 1104–1112, doi:10.3762/bjnano.7.103

• of detection (LOD) of 3.22 × 10−6 M. The regression relationship is expressed as The lower limit of detection was calculated from the calibration data using the following equation: where s is the standard deviation of the intercept and m is the slope of the regression line. The analytical performance

• additions of standard solution of GA. On plotting the peak current versus GA concentration, the corresponding calibration plot was obtained (inset of Figure 6). It is found that the peak current of GA correlates linearly with the GA concentration in the range of 4.975 × 10−6 to 3.381 × 10−5 M with a limit

Electrochemical behavior of polypyrrol/AuNP composites deposited by different electrochemical methods: sensing properties towards catechol

• Celia García-Hernández,
• Cristina García-Cabezón,
• Cristina Medina-Plaza,
• Fernando Martín-Pedrosa,
• Yolanda Blanco,
• José Antonio de Saja and
• María Luz Rodríguez-Méndez

Beilstein J. Nanotechnol. 2015, 6, 2052–2061, doi:10.3762/bjnano.6.209

• CP in 1·10−5 to 1·10−3 mol/L catechol solutions. A linear increase in the intensity of the peaks with the concentration was observed in the studied range. The limit of detection (LOD) was calculated from the calibration curves following the “3sd/m” criterion. As observed in Table 2, the LODs were in

Optimized design of a nanostructured SPCE-based multipurpose biosensing platform formed by ferrocene-tethered electrochemically-deposited cauliflower-shaped gold nanoparticles

• Wicem Argoubi,
• Maroua Saadaoui,
• Sami Ben Aoun and
• Noureddine Raouafi

Beilstein J. Nanotechnol. 2015, 6, 1840–1852, doi:10.3762/bjnano.6.187

• recognition sites of the immunosensor. The plot of potential variation vs the amount of Ag gives a straight line (R2 = 0.97871) (Figure 4d) which confirmed the reproducibility of the measurements [35]. The limit of detection (LoD) and the limit of quantification (LoQ) were calculated using the formulae LoD

Glassy carbon electrodes modified with multiwalled carbon nanotubes for the determination of ascorbic acid by square-wave voltammetry

• Sushil Kumar and
• Victoria Vicente-Beckett

Beilstein J. Nanotechnol. 2012, 3, 388–396, doi:10.3762/bjnano.3.45

• electrode. Table 1 also shows that better repeatability and reproducibility of both peak currents and peak potentials were observed on the modified GCE compared to the bare GCE, demonstrating clearly that the modified electrode was protected from fouling by the Nafion membrane. The limit of detection (LOD